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Showing 1-50 of 5,549 articles

Mechanistic insights and emerging therapeutic strategies targeting endothelial dysfunction in cardiovascular diseases
Kyung-Sun Heo
Lan Phuong Phan
Yujin Jin
Review 29 April 2025
PET tracer development for imaging α-synucleinopathies
Mohammad Maqusood Alam
Sun Hak Lee
Sang-Yoon Lee
Review 14 April 2025
A review on bacteria-derived antioxidant metabolites: their production, purification, characterization, potential applications, and limitations
Nazli Pinar Arslan
Fakhrul Azad
Mesut Taskin
Review Open access 10 April 2025
The dynamic roles of macrophages extracellular traps (METs) in immune regulation
Yunjin Shin
Hanyoung Bae
Inmoo Rhee
Review 05 April 2025
The inhibition of endothelial DLL4-NOTCH1 signaling by 2'-hydroxyflavanone enhances anti-PD-1 therapy in melanoma
Jihye You
Seunghwan Ha
You Mie Lee
Research Article 02 April 2025
Covalent organic frameworks in cancer theranostics: advancing biomarker detection and tumor-targeted therapy
Sonia Iranpour
Amir Abrishami
Amir Sh. Saljooghi
Review 22 March 2025 Pages: 183 - 211
Impact of binge drinking on alcoholic liver disease
Jisoo Kang
Seol Hee Park
Wonhyo Seo
Review 04 March 2025 Pages: 212 - 223
A novel 11β-HSD1 inhibitor ameliorates liver fibrosis by inhibiting the notch signaling pathway and increasing NK cell population
Ji Eun Kim
Yun Kim
Dae Won Jun
Research Article 15 February 2025 Pages: 166 - 180
Retraction Note: Anti-inflammatory effect of atorvastatin on vascular reactivity and insulin resistance in fructose fed rats
Mona F. Mahmoud
Mohamed El-Nagar
Hany M. El-Bassossy
Retraction Note 12 February 2025 Pages: 251 - 251
Discovery of novel naphthalene-based diarylamides as pan-Raf kinase inhibitors with promising anti-melanoma activity: rational design, synthesis, in vitro and in silico screening
Ahmed Elkamhawy
Usama M. Ammar
Kyeong Lee
Research Article Open access 08 February 2025 Pages: 150 - 165
Tumor microenvironment regulation by reactive oxygen species-mediated inflammasome activation
Jeong-Hoon Jang
Do-Hee Kim
Kyung-Soo Chun
Review 31 January 2025 Pages: 115 - 131
Physiologically based pharmacokinetic (PBPK) modeling of gliclazide for different genotypes of CYP2C9 and CYP2C19
Hye-Jung Park
Sang-Ho Lee
Chang-Ik Choi
Research Article 06 January 2025 Pages: 234 - 250
Canine mammary tumors as a promising adjunct preclinical model for human breast cancer research: similarities, opportunities, and challenges
Zeeshan Ahmad Bhutta
Kyung-Chul Choi
Review 03 January 2025 Pages: 43 - 61
Retraction Note: MiR-338-5p ameliorates pathological cardiac hypertrophy by targeting CAMKIIδ
Kailong Li
Yuedong Lin
Cong Li
Retraction Note 02 January 2025 Pages: 181 - 181
Effects of fluconazole on the pharmacokinetics of celecoxib and its carboxylic acid metabolite in different CYP2C9 genotypes
Chang-Keun Cho
Pureum Kang
Seok-Yong Lee
Research Article 27 December 2024 Pages: 224 - 233
Immunosenescence and age-related immune cells: causes of age-related diseases
Nam-Hee Kim
So-Jin Sim
Yong-Hyun Han
Review 26 December 2024 Pages: 132 - 149
Three new xanthones and other anti-inflammatory components from the aerial parts of Hypericum beanii
Wei Ma
Fu-Cai Ren
Ning Li
Research Article 18 December 2024 Pages: 89 - 101
Ideal animal models according to multifaceted mechanisms and peculiarities in neurological disorders: present and challenges
Shrawani Lamichhane
Jo-Eun Seo
Sangkil Lee
Review 18 December 2024 Pages: 62 - 88
Cell membrane chromatography relative competitive method for the accurate determination of relative K_D values of drug-receptor interactions
Panpan Lei
Weina Ma
Langchong He
Research Article 10 December 2024 Pages: 102 - 114
Exploring β-caryophyllene: a non-psychotropic cannabinoid's potential in mitigating cognitive impairment induced by sleep deprivation
Cher Ryn Lim
Satoshi Ogawa
Yatinesh Kumari
Review 09 December 2024 Pages: 1 - 42
Biological insights and therapeutic potential of Glycyrrhiza uralensis and its bioactive compounds: an updated review
Sibhghatulla Shaikh
Khurshid Ahmad
Inho Choi
Review 03 December 2024 Pages: 871 - 892
Curcumin targets CXCL16-mediated podocyte injury and lipid accumulation in diabetic kidney disease treatment
Ying Chen
Jun Tao
Aili Cao
Research Article 28 November 2024 Pages: 924 - 939
Exploring NNMT: from metabolic pathways to therapeutic targets
Jeongwoo Park
Eun Jin Shin
Kyu Min Kim
Review 28 November 2024 Pages: 893 - 913
Prediction of human pharmacokinetic parameters incorporating SMILES information
Jae-Hee Kwon
Ja-Young Han
Myeong Gyu Kim
Research Article 26 November 2024 Pages: 914 - 923
Donepezil improves skeletal muscle insulin resistance in obese mice via the AMPK/FGF21-mediated suppression of inflammation and ferroptosis
Hyeon Ji Gwon
Wonjun Cho
Tae Woo Jung
Research Article 24 November 2024 Pages: 940 - 953
Saponins as potential novel NLRP3 inflammasome inhibitors for inflammatory disorders
Jiamei Tang
Yaxiao Liu
Yuze Li
Review 16 November 2024 Pages: 757 - 792
Modulating versatile pathways using a cleavable PEG shell and EGFR-targeted nanoparticles to deliver CRISPR-Cas9 and docetaxel for triple-negative breast cancer inhibition
Yu-Li Lo
Ci-Jheng Hong
Ching-Ping Yang
Research Article Open access 01 November 2024 Pages: 829 - 853
Ginsenoside Rg3 activates the immune function of CD8+ T cells via circFOXP1-miR-4477a-PD-L1 axis to induce ferroptosis in gallbladder cancer
Zhipeng Ye
Jianfeng Ding
Keren Wu
Research Article 28 October 2024 Pages: 793 - 811
Potential effects of a human milk oligosaccharide 6′-sialyllactose on angiotensin II-induced aortic aneurysm via p90RSK/TGF-β/SMAD2 signaling pathway
Thuy Le Lam Nguyen
Dung Van Nguyen
Kyung-Sun Heo
Research Article 27 October 2024 Pages: 854 - 869
Akt-activated GSK3β inhibitory peptide effectively blocks tau hyperphosphorylation
Eunjin Lee
Yujeong Lee
Jaewon Lee
Research Article 26 September 2024 Pages: 812 - 828
Paeonia genus: a systematic review of active ingredients, pharmacological effects and mechanisms, and clinical applications for the treatment of cancer
Xinrui Zhou
Aikebaier Alimu
Zhe Lin
Review 22 September 2024 Pages: 677 - 695
Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis therapy
Swati Rajput
Chirag Kulkarni
Naibedya Chattopadhyay
Research Article 29 July 2024 Pages: 736 - 755
E3 ubiquitin ligase RNF180 mediates the ALKBH5/SMARCA5 axis to promote colon inflammation and Th17/Treg imbalance in ulcerative colitis mice
Kailing Wang
Fan Liu
Miao Ouyang
Research Article 27 July 2024 Pages: 645 - 658
Antitumor activity of Polygonatum sibiricum polysaccharides
Weiwei Lai
Qian Ning
Shengsong Tang
Review 26 July 2024 Pages: 696 - 708
Pentacyclic triterpenes, potential novel therapeutic approaches for cardiovascular diseases
Dewei Peng
Aizan Wang
Li Lin
Review 24 July 2024 Pages: 709 - 735
C-phycocyanin reinforces autophagy to block pulmonary fibrogenesis by inhibiting lncIAPF biogenesis
Wenjie Hu
Yujie Wang
Songzi Zhang
Research Article Open access 22 July 2024 Pages: 659 - 674
Dual roles of myeloid-derived suppressor cells in various diseases: a review
Mahesh Raj Nepal
Sajita Shah
Kyu-Tae Kang
Review 15 July 2024 Pages: 597 - 616
Implications of inflammatory cell death-PANoptosis in health and disease
Hyun Bae
Yeonseo Jang
Joo-Hui Han
Review 10 July 2024 Pages: 617 - 631
Dihydroartemisinin inhibits follicular helper T and B cells: implications for systemic lupus erythematosus treatment
Xiaoyi Shi
Tao Liao
Yunfeng Pan
Research Article 08 July 2024 Pages: 632 - 644
Correction: Antibody drug conjugates as targeted cancer therapy: past development, present challenges and future opportunities
Ritwik Maiti
Bhumika Patel
Nirav Dhanesha
Correction 26 June 2024 Pages: 675 - 675
Challenges and opportunities of developing small-molecule therapies for age-related macular degeneration
Xiang Fei
Sooyun Jung
Seung-Yong Seo
Review 20 June 2024 Pages: 538 - 557
Interplay between YAP/TAZ and metabolic dysfunction-associated steatotic liver disease progression
Na Young Lee
Myeung Gi Choi
Ja Hyun Koo
Review Open access 14 June 2024 Pages: 558 - 570
Antibacterial properties of natural products from marine fungi reported between 2012 and 2023: a review
Ping Wang
Xiaomei Huang
Tingting Wang
Review 08 June 2024 Pages: 505 - 537
Exploring molecular mechanisms, therapeutic strategies, and clinical manifestations of Huntington’s disease
Alaa Shafie
Amal Adnan Ashour
Md. Imtaiyaz Hassan
Review 19 May 2024 Pages: 571 - 595
Phytochemical and pharmacological properties of the genus Tamarix: a comprehensive review
Fangjie Li
Wenli Xie
Xianjun Fu
Review 15 May 2024 Pages: 410 - 441
Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets
Yajing Guo
Xuling Peng
Feng Qiu
Review 13 May 2024 Pages: 377 - 409
Continuous TNF-α exposure in mammary epithelial cells promotes cancer phenotype acquisition via EGFR/TNFR2 activation
Jin-Hee Lee
Steffanus Pranoto Hallis
Mi-Kyoung Kwak
Research Article 11 May 2024 Pages: 465 - 480
PBPK modeling to predict the pharmacokinetics of venlafaxine and its active metabolite in different CYP2D6 genotypes and drug–drug interactions with clarithromycin and paroxetine
Chang-Keun Cho
Pureum Kang
Chang-Ik Choi
Research Article 25 April 2024 Pages: 481 - 504
Combination therapy involving HSP90 inhibitors for combating cancer: an overview of clinical and preclinical progress
Yajun Liu
Chenyao Li
Shutao Tan
Review 17 April 2024 Pages: 442 - 464
TNF receptor 2 knockout mouse had reduced lung cancer growth and schizophrenia-like behavior through a decrease in TrkB-dependent BDNF level
In Jun Yeo
Ji Eun Yu
Jin Tae Hong
Research Article Open access 09 April 2024 Pages: 341 - 359

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