Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons Sebastiaan MoonenMarta J. KoperDietmar Rudolf Thal Original Paper 09 December 2022 Pages: 175 - 195
Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies Frederique J. Hart de RuyterTjado H. J. MorremaJeroen J. M. Hoozemans Original Paper 08 December 2022 Pages: 197 - 218
Brain and spinal cord arteriolosclerosis and its associations with cerebrovascular disease risk factors in community-dwelling older adults Shahram OveisgharanNamhee KimAron S. Buchman Original Paper 05 December 2022 Pages: 219 - 233
Tuberous sclerosis complex is associated with a novel human tauopathy Ji-Hye L. HwangOlga S. PerloffWilliam W. Seeley Original Paper 05 December 2022 Pages: 1 - 12
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts Martin MynarekDenise ObrechtTill Milde Original Paper Open access 02 December 2022 Pages: 97 - 112
Correction to: Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease YuHong FuLiche ZhouGlenda M. Halliday Correction Open access 27 November 2022 Pages: 157 - 157
Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification Michaela-Kristina KeckMartin SillDavid T. W. Jones Original Paper Open access 27 November 2022 Pages: 49 - 69
Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement Gábor BedicsMonika CsókaBálint Scheich Correspondence Open access 23 November 2022 Pages: 153 - 156
Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials Nicholas G. Gottardo Correspondence Open access 20 November 2022 Pages: 145 - 147
Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation Karin M. ForsbergKarin S. GraffmoPeter M. Andersen Original Paper Open access 16 November 2022 Pages: 13 - 28
RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation Yoon A. KimTohid SiddiquiIsmael Santa-Maria Original Paper Open access 10 November 2022 Pages: 29 - 48
More than a co-incidence? Comment on: Amyotrophic lateral sclerosis is over‐represented in two Huntington’s disease brain bank cohorts: further evidence to support genetic pleiotropy of pathogenic HTT gene expansion Hannah S. BakelsStephanie FeleusSusanne T. de Bot Correspondence Open access 06 November 2022 Pages: 257 - 258
NTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target L. S. Hiemcke-JiwaM. T. MeisterL. A. Kester Correspondence Open access 04 November 2022 Pages: 149 - 152
Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1 Patrick J. CiminoCourtney KetchumKenneth Aldape Original Paper 22 October 2022 Pages: 71 - 82
Loss of function variants in DNAJB4 cause a myopathy with early respiratory failure Conrad C. WeihlAna TöpfVolker Straub Original Paper 20 October 2022 Pages: 127 - 143
Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours Alice MétaisYassine BouchouchaArnault Tauziède-Espariat Original Paper Open access 20 October 2022 Pages: 83 - 95
Professor Charles Duyckaerts (1951–2022) Danielle D Seilhean Obituary 19 October 2022 Pages: 1061 - 1062
Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions Zhichao WuSharika RajanKenneth Aldape Correspondence 06 October 2022 Pages: 1175 - 1178
Neuropathology of central nervous system involvement in TTR amyloidosis Ricardo TaipaLuísa SousaTeresa Coelho Original Paper Open access 06 October 2022 Pages: 113 - 126
Assessment of PABPN1 nuclear inclusions on a large cohort of patients and in a human xenograft model of oculopharyngeal muscular dystrophy Fanny RothJamila DhiabCapucine Trollet Original Paper Open access 05 October 2022 Pages: 1157 - 1170
Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas Tobias GoschzikMartin MynarekTorsten Pietsch Original Paper Open access 01 October 2022 Pages: 1143 - 1156
The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers Nazanin TatariShahbaz KhanThomas Kislinger Original Paper 30 September 2022 Pages: 1127 - 1142
Correction to: Flow blockage disrupts cilia-driven fluid transport in the epileptic brain Regina J. FaubelVeronica S. Santos CanellasCecilia W. Lo Correction 29 September 2022 Pages: 1189 - 1189
Prognostic significance of chromosome arm 1q gain and methylation class in molecularly defined diffuse leptomeningeal glioneuronal tumor Jason ChiangDaniel C. MoreiraLarissa V. Furtado Correspondence Open access 29 September 2022 Pages: 1185 - 1187
Genetic and epigenetic profiling identifies two distinct classes of spinal meningiomas Franz L. RicklefsKrystian D. FitaSven O. Eicker Correspondence Open access 27 September 2022 Pages: 1057 - 1059
Clinicopathological and molecular characterization of three cases classified by DNA-methylation profiling as “Glioneuronal Tumors, NOS, Subtype A” Arnault Tauziède-EspariatVolodia-Dangouloff-Rosthe RENOCLIP-LOC Correspondence 19 September 2022 Pages: 1179 - 1183
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD Federica PilottoAlexander SchmitzSmita Saxena Original Paper Open access 19 September 2022 Pages: 939 - 966
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo Rachel E. LackieAline S. de MirandaMarco A. M. Prado Original Paper Open access 19 September 2022 Pages: 881 - 910
In memoriam, Roy Weller (1938–2022) Roxana O. CarareBritta EngelhardtRaj Kalaria Obituary 19 September 2022 Pages: 803 - 806
Expanding the spectrum of amyloid-β plaque pathology: the Down syndrome associated ‘bird-nest plaque’ Shojiro IchimataIvan Martinez-ValbuenaGabor G. Kovacs Correspondence 16 September 2022 Pages: 1171 - 1174
Cross-regional homeostatic and reactive glial signatures in multiple sclerosis Tim TrobischAmel ZuljiLucas Schirmer Original Paper Open access 16 September 2022 Pages: 987 - 1003
TREM2 risk variants are associated with atypical Alzheimer’s disease Boram KimEunRan SuhEdward B. Lee Original Paper 16 September 2022 Pages: 1085 - 1102
Concussion leads to widespread axonal sodium channel loss and disruption of the node of Ranvier Hailong SongPrzemyslaw P. McEwanDouglas H. Smith Original Paper 15 September 2022 Pages: 967 - 985
A CHCHD6–APP axis connects amyloid and mitochondrial pathology in Alzheimer’s disease Yutong ShangXiaoyan SunXin Qi Original Paper Open access 14 September 2022 Pages: 911 - 938
Receptor clustering and pathogenic complement activation in myasthenia gravis depend on synergy between antibodies with multiple subunit specificities Natalie RoseSebastian HoldermannTobias Derfuss Original Paper Open access 08 September 2022 Pages: 1005 - 1025
Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases Philipp SieversMartin SillFelix Sahm Correspondence Open access 07 September 2022 Pages: 1049 - 1052
Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma Robert SiddawayLaura CantyCynthia Hawkins Original Paper Open access 07 September 2022 Pages: 1027 - 1048
Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration Lucia A. A. GianniniDaniel T. OhmNetherlands Brain Bank Original Paper Open access 06 September 2022 Pages: 1065 - 1084
Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers Iris E. JansenSven J. van der LeeWiesje van der Flier Original Paper Open access 06 September 2022 Pages: 821 - 842
Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease YuHong FuLiche ZhouGlenda M. Halliday Original Paper Open access 02 September 2022 Pages: 861 - 879
Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease Jolien PerneelRosa Rademakers Review Open access 02 September 2022 Pages: 807 - 819
Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging Abris GilvesyEvelina HusenCsaba Adori Original Paper Open access 30 August 2022 Pages: 651 - 676
Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein Sara A. M. HolecJisoo LeeAmanda L. Woerman Original Paper 26 August 2022 Pages: 677 - 690
Transmission of cervid prions to humanized mice demonstrates the zoonotic potential of CWD Samia HannaouiIrina ZemlyankinaSabine Gilch Original Paper Open access 22 August 2022 Pages: 767 - 784
Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas Helin DoganChristina BlumeFelix Sahm Correspondence Open access 19 August 2022 Pages: 799 - 802
Selective tau seeding assays and isoform-specific antibodies define neuroanatomic distribution of progressive supranuclear palsy pathology arising in Alzheimer’s disease David G. CoughlinVanessa S. GoodwillAnnie Hiniker Correspondence Open access 18 August 2022 Pages: 789 - 792
DNA methylation analysis of archival lymphoreticular tissues in Creutzfeldt–Jakob disease Fernando GuntoroEmmanuelle ViréSimon Mead Correspondence Open access 18 August 2022 Pages: 785 - 787
Molecular classification and outcome of children with rare CNS embryonal tumors: results from St. Jude Children’s Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials Anthony P. Y. LiuSandeep K. DhandaGiles W. Robinson Original Paper 18 August 2022 Pages: 733 - 746
Flow blockage disrupts cilia-driven fluid transport in the epileptic brain Regina J. FaubelVeronica S. Santos CanellasCecilia W. Lo Original Paper 18 August 2022 Pages: 691 - 706
